1100766-76-4Relevant academic research and scientific papers
Synthesis of novel tetrahydroisoquinoline bronchodilators
Dalence-Guzmán, Maria F.,Toftered, J?rgen,Oltner, Viveca Thornqvist,Wensbo, David,Johansson, Martin H.
scheme or table, p. 4999 - 5003 (2010/10/05)
The synthesis and bronchorelaxing effects of a series of novel tetrahydroisoquinoline amides are described. The compounds were evaluated for their ability to relax LTD4 contracted isolated human small airways ex-vivo. Several compounds demonstrated highly
NOVEL BRONCHODILATING ISOQUINOLINE AMIDES
-
Page/Page column 38, (2009/03/07)
The invention relates to novel compounds having the general formula I, and which compounds are useful to manufacture a medicament to treat a disorder or disease characterized by bronchoconstriction, e.g. COPD and asthma, and vasoconstriction, e.g. hypertension.
