1100829-46-6

Basic information

• Product Name: 2'-O-(2-methoxyethyl)-3',5'-di-O-benzoyl-5-iodouridine
• Synonyms: 2'-O-(2-methoxyethyl)-3',5'-di-O-benzoyl-5-iodouridine
• CAS NO: 1100829-46-6
• Molecular Weight: 636.397
• Mol File: 1100829-46-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-O-(2-methoxyethyl)-3',5'-di-O-benzoyl-5-iodouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(2-methoxyethyl)-3',5'-di-O-benzoyl-5-iodouridine(1100829-46-6)
• EPA Substance Registry System: 2'-O-(2-methoxyethyl)-3',5'-di-O-benzoyl-5-iodouridine(1100829-46-6)

Safety Data

• Hazardous Substances Data: 1100829-46-6(Hazardous Substances Data)

Upstream product

• 1251827-52-7 1-O-acetyl-2-O-(2-methoxyethyl)-3,5-di-O-benzoyl-D-ribofuranoside 
• 696-07-1 5-iodouracil 

Relevant articles and documents

Synthesis and properties of triplex-forming oligonucleotides containing 2′-O-(2-methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine

2′-O-(2-Methoxyethyl)-5-(3-aminoprop-1-ynyl)-uridine phosphoramidite (MEPU) has been synthesized from d-ribose and 5-iodouracil and incorporated into triplex-forming oligonucleotides (TFOs) by automated solid-phase oligonucleotide synthesis. The TFOs gave very high triplex stability with their target duplexes as measured by ultraviolet/fluorescence melting and DNase I footprinting. The incorporation of MEPU into TFOs renders them resistant to degradation by serum nucleases.