1101147-31-2

Upstream product

• 496-12-8 isoindoline 
• 1228311-56-5 tert-butyl 5-iodo-2,3-dioxo-2,3-dihydroindole-1-carboxylate 

Downstream Products

• 1367454-59-8 {2-amino-6-[2-((S)-2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-60-1 {2-amino-6-[2-((R)-2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-61-2 {2-amino-6-[4-fluoro-2-(2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-62-3 {2-amino-6-[5-fluoro-2-(2-methylpyrrolidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-63-4 methyl 1-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]-benzyl}pyrrolidine-2-carboxylate 
• 1367454-64-5 1-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzyl}-pyrrolidine-2-carboxylic acid 
• 1367454-65-6 N-methyl-1-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]-benzyl}pyrrolidine-2-carboxamide 
• 1367454-66-7 N-(2-hydroxyethyl)-1-{2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzyl}pyrrolidine-2-carboxamide 
• 1367454-67-8 {2-amino-6-[2-(4-hydroxypiperidin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-68-9 {2-amino-6-[5-fluoro-2-(4-methylpiperazin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-69-0 {2-amino-6-[4-fluoro-2-(4-methylpiperazin-1-ylmethyl)phenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-70-3 {2-amino-6-[2-(methylethylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-71-4 {2-amino-6-[2-(diethylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 
• 1367454-72-5 {2-amino-6-[2-(tert-butylaminomethyl)-4,5-difluorophenyl]quinazolin-4-yl}-(1,3-dihydroisoindol-2-yl)methanone 

Relevant academic research and scientific papers

PHENYLQUINAZOLINE DERIVATIVES

Novel quinazolinamide derivatives of the formula (I), in which R1-R43 and X have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

QUINAZOLINAMIDE DERIVATIVES

Novel quinazolinamide derivatives of the formula (I), in which R1-R5 and X have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the in

Quinazolinamide derivatives

Novel quinazolinamide derivatives of the formula (I), in which R1-R3 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.