1101186-75-7Relevant articles and documents
Diastereoselective preparation of substituted δ-valerolactones. synthesis of (3R,4S)-And (3R,4R)-simplactones
Osorio-Lozada, Antonio,Olivo, Horacio F.
, p. 1360 - 1363 (2009)
The syntheses of simplactones (3R,4S)-1 and (3R,4R)-2 were achieved in 5 steps from N-acyl thiazolidinethione chiral auxiliaries. The syntheses feature a double diastereoselective acetate aldol reaction solely controlled by the chirality of the auxiliary.