1101186-75-7Relevant academic research and scientific papers
Diastereoselective preparation of substituted δ-valerolactones. synthesis of (3R,4S)-And (3R,4R)-simplactones
Osorio-Lozada, Antonio,Olivo, Horacio F.
, p. 1360 - 1363 (2009)
The syntheses of simplactones (3R,4S)-1 and (3R,4R)-2 were achieved in 5 steps from N-acyl thiazolidinethione chiral auxiliaries. The syntheses feature a double diastereoselective acetate aldol reaction solely controlled by the chirality of the auxiliary.
Synthesis of coronafacic acid via TBAF-assisted elimination of the mesylate and its conversion to the isoleucine conjugate
Kosaki, Yusuke,Ogawa, Narihito,Wang, Qian,Kobayashi, Yuichi
, p. 4232 - 4235 (2011)
An aldol reaction followed by elimination of the derived mesylate was used to construct the side chain that was designed to afford the cyclohexene ring of coronafacic acid via intramolecular alkylation. Elimination of the mesylate proceeded with TBAF. The
