110143-46-9Relevant academic research and scientific papers
Nitrogen-bridged conformationally constrained etorphine analogues. Synthesis and biological evaluation
Maurer,Rapoport
, p. 2016 - 2026 (2007/10/02)
Three N-C8-bridged analogues 4-6 of the opiate etorphine (3) were synthesized and evaluated for opiate agonism and antagonism. In each case ring closure was effected by intramolecular N-alkylation with a suitably developed C8 side chain. Another key synth
