110144-97-3

Upstream product

• 108-98-5 thiophenol 
• 613-54-7 2-Bromo-2'-acetonaphthone 

Downstream Products

• 1380501-97-2 methylphenylsulfonium 2-naphthacylide 
• 7417-81-4 benzyl phenyl sulfoxide 
• 882-33-7 diphenyldisulfane 
• 93-08-3 methyl 2-naphthyl ketone 
• 1192108-53-4 2-[1-(2,3,4-trimethoxyphenyl)vinyl]naphthalene 

Relevant academic research and scientific papers

Gold-catalyzed carbene transfer to alkynes: Access to 2,4-disubstituted furans

Furans of gold: The first example of a gold-catalyzed intermolecular addition of carbon ylides to terminal alkynes is reported (see scheme; DCE=dichloroethane, Tf=trifluoromethanesulfonyl). Subsequent intramolecular trapping of the generated gold carbene completes a formal [3+2] cycloaddition, which represents a novel synthesis of 2,4-disubstituted furans. Copyright

A route to benzylic arylsulfoxides from β-ketosulfoxides

The K2CO3-mediated benzylation of β-ketosulfoxides 4 with 2.0?equiv of benzylic halides 5 affords benzylic arylsulfoxides 6 in moderate yields along with trace amounts of chalcones 7. The products 6 are assumed to form in situ intermediates of sulfenate anions from β-ketosulfoxides which are commonly involved in carbon–sulfur bond formation. A plausible mechanism has been proposed.

Visible light mediated reductions of ethers, amines and sulfides

Visible light-mediated photoredox catalysis enables the chemoselective reduction of activated carbon–heteroatom bonds as a function of reduction potential. The expansion of the scope of C–X bond reductions towards less activated motifs, such as ethers, amines and sulfides, is important to both organic synthesis and macromolecular degradation method development. In the present report, exploration of photoredox catalysis in alcoholic solvents mediated a decrease in the super-stoichiometric use of iPr2NEt and HCO2H in the reduction of α-keto ethers, amines and sulfides. Additionally, in the absence of fragmentation, [Formula presented] bond formation was afforded, suggesting an intermediate ketyl radicals are present in these transformations.

Diarylmethylidenefuran derivatives and their uses in therapeutics

The present invention relates to the derivatives of the formula STR1 and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.