110164-37-9Relevant academic research and scientific papers
Thiophene Systems. 11. The Synthesis of Novel Thieno Tricyclic Ring Systems
Russell, Roland K.,Rampulla, Richard A.,Nievelt, Caroline E. van,Klaubert, Dieter H.
, p. 1761 - 1770 (2007/10/02)
The synthesis of thieno tricyclic compounds is described.The N-1 alkylation of I produced the alkanoic ester precursors.After hydrolysis, the corresponding carboxylic acids were cyclized to the title compounds II.This cyclization step was accomp
Thiophene Systems. 9. Thienopyrimidinedione Derivatives as Potential Antihypertensive Agents
Russell, Ronald K.,Press, Jeffrey B.,Rampulla, Richard A.,McNally, James J.,Falotico, Robert,et al.
, p. 1786 - 1793 (2007/10/02)
A series of thieno-, thieno-, and thienopyrimidine-2,4-diones with (phenylpiperazinyl)alkyl substitution at N-3 have been synthesized and evaluated for antihypertensive effects in spontaneously hypertensive rats (SHR).These 49 compoun
Thienopyrimidine-2,4-dione derivatives and intermediates thereof
-
, (2008/06/13)
The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are us
