110164-84-6

Basic information

• Product Name: (3-BROMO-4,5-DIHYDRO-ISOXAZOL-5-YL)-METHANOL
• Synonyms: (3-BROMO-4,5-DIHYDRO-ISOXAZOL-5-YL)-METHANOL
• CAS NO: 110164-84-6
• Molecular Formula: C4H6BrNO2
• Molecular Weight: 180
• Mol File: 110164-84-6.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-BROMO-4,5-DIHYDRO-ISOXAZOL-5-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BROMO-4,5-DIHYDRO-ISOXAZOL-5-YL)-METHANOL(110164-84-6)
• EPA Substance Registry System: (3-BROMO-4,5-DIHYDRO-ISOXAZOL-5-YL)-METHANOL(110164-84-6)

Safety Data

• Hazardous Substances Data: 110164-84-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 3113, 1992 DOI: 10.1016/S0040-4039(00)79827-3

Upstream product

• 129097-92-3 3-bromo-5-(hydroxymethyl)-Δ²-isoxazoline 
• 918440-90-1 ((S)-3-bromo-4,5-dihydroisoxazol-5-yl)methyl acetate 
• 140384-87-8 Butyric acid (S)-3-bromo-4,5-dihydro-isoxazol-5-ylmethyl ester 
• 140176-87-0 (+/-)-3-bromo-5-(hydroxymethyl)-δ²-isoxazoline butyrate 
• 128993-10-2 (5S)-5-<(1R)-1,2-dihydroxyethyl>-3-bromo-Δ²-isoxazoline 
• 108-05-4 vinyl acetate 
• 128993-16-8 (5R)-5-<(1R)-1,2-dihydroxyethyl>-3-bromo-Δ²-isoxazoline 
• 13146-23-1 copper(I) phenylacetylenide 
• 74213-24-4 N-dibromomethylidenehydroxylamine 
• 107-18-6 allyl alcohol 

Downstream Products

• 128993-18-0 (5R)-3-Bromo-5-hydroxymethyl-Δ²-isoxazoline 
• 128993-17-9 (5S)-3-Bromo-5-hydroxymethyl-Δ²-isoxazoline 
• 918440-90-1 ((S)-3-bromo-4,5-dihydroisoxazol-5-yl)methyl acetate 
• 140384-88-9 Butyric acid (R)-3-bromo-4,5-dihydro-isoxazol-5-ylmethyl ester 
• 140384-87-8 Butyric acid (S)-3-bromo-4,5-dihydro-isoxazol-5-ylmethyl ester 
• 143005-79-2 (S)-(3-bromo-4,5-dihydroisoxazol-5-yl)methanamine 
• 143005-81-6 (R)-(3-bromo-4,5-dihydroisoxazol-5-yl)methanamine 
• 152611-10-4 (S)-2-Cyclohexyl-5-hydroxymethyl-isoxazolidin-3-one 
• 129097-85-4 (5S)-3-benzyloxy-5-hydroxymethyl-Δ²-isoxazoline 
• 129097-84-3 (5R)-3-benzyloxy-5-hydroxymethyl-Δ²-isoxazoline 
• 128993-09-9 (RS)-3-benzyloxy-5-(hydroxymethyl)-Δ²-isoxazoline 
• 83527-35-9 S-3,4-dihydroxy butyronitrile 

Relevant articles and documents

The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds

Target analysis of acivicin derived 3-halodihydroisoxazoles scaffolds in living non-pathogenic and pathogenic bacteria.

Tandem synthesis of 3-halo-5-substituted isoxazoles from 1-copper(I) alkynes and dihaloformaldoximes

A tandem synthesis of 3-halo-5-substituted isoxazoles has been developed from 1-copper(I) alkynes and dihaloformaldoximes under base-free conditions. Thus, 1,3-dipolar cycloaddition and all its drawbacks can now be avoided completely.

BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional hetercyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.