110167-24-3Relevant academic research and scientific papers
Hexahydro-1,4-oxazepines. Part 1. Synthesis by Morpholine Ring Expansion
Brown, George R.,Foubister, Alan J.,Wright, Brian
, p. 553 - 556 (2007/10/02)
Reaction of 4-benzyl-3-chloromethylmorpholine with phenoxide anions led not only to 4-benzyl-3-phenoxymethyl morpholines, but substantial amounts of 4-benzyl-6-phenoxy-1,4-oxazepanes.The ring expansion reaction is explained in terms of neighbouring group participation, leading to an ambient aziridinium intermediate.
