110168-56-4

Upstream product

• 110168-53-1 5-iodo-4-oxo-4H-1,3-dioxine-2-spirocyclohexane 
• 536-74-3 phenylacetylene 
• 110168-48-4 6-acetoxy-5-bromo-4-oxo-1,3-dioxine-2-spirocyclohexane 
• 94691-90-4 4-oxo-1,5-dioxaspiro<5.5>undec-2-ene 
• 110168-52-0 5-bromo-4-oxo-4H-1,3-dioxine-2-spirocyclohexane 

Relevant academic research and scientific papers

Synthesis of 1,3-Dioxin-4-ones and Their Use in Synthesis. XIII. Synthesis of 5-Halo-1,3-dioxin-4-ones and Their Conversion to 5-Alkyl Derivatives

A novel method for the introduction of an alkyl group at the 5-position of 1,3-dioxin-4-ones is described.Reaction of 5,6-unsubstituted 1,3-dioxin-4-ones with N-halosuccinimide in acetic acid followed by treatment with a base gave 5-bromo- and 5-iodo-1,3-