1101770-99-3Relevant academic research and scientific papers
Structure-activity relationships of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the treatment of cough
Yang, Shu-Wei,Ho, Ginny,Tulshian, Deen,Greenlee, William J.,Fernandez, Xiomara,McLeod, Robbie L.,Eckel, Stephen,Anthes, John
scheme or table, p. 6340 - 6343 (2009/09/06)
A series of 3-axial-aminomethyl-N-benzhydryl-nortropane analogs have been synthesized and identified to bind to the nociceptin receptor with high affinity. Many of these analogs showed high binding selectivity over classic opioid receptors such as μ recep
