1101825-01-7Relevant articles and documents
Oxidative esterification of aldehydes using mesoionic 1,2,3-triazolyl carbene organocatalysts
Berry, Matthew T.,Castrejon, Disnay,Hein, Jason E.
, p. 3676 - 3679 (2014)
The synthesis and catalytic activity of a new class of 1,2,3-triazolyl N-heterocyclic carbene organocatalysts is described. These new catalysts chemoselectively facilitate the oxidative esterification of aldehydes. NMR acidity studies show an inverse correlation between triazolium acidity and reactivity. Kinetic studies show that the resting state of the catalyst involves a NHC-aldehyde adduct. A catalytically active intermediate was synthesized and characterized by X-ray diffraction as the initial carbene-aldehyde adduct.
CYCLOADDITION OF AZIDES AND ALKYNES
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Page/Page column 8, (2009/04/24)
This invention provides a process which comprises contacting, in a reaction zone, at least one organic azide, at least one alkyne, and at least one N-heterocyclic carbene copper compound in which the ligands are either (i) a halide and an N-heterocyclic c