1101858-63-2Relevant academic research and scientific papers
Identification of pharmacophore model, synthesis and biological evaluation of N-phenyl-1-arylamide and N-phenylbenzenesulfonamide derivatives as BACE 1 inhibitors
Huang, Wenhai,Yu, Haiping,Sheng, Rong,Li, Jia,Hu, Yongzhou
experimental part, p. 10190 - 10197 (2009/04/07)
The pharmacophore model of arylpiperazine amide derivatives was built using Discovery Studio 2.0 software package and the best pharmacophore model (Hypo 1) was validated by Enrichment and ROC method (EF at 2%, 5% and 10% are 30.6, 12.2 and 7.7; AUC of the
