1101882-05-6Relevant articles and documents
Atroposelective radical aryl migration reactions from sulfur to carbon
Schulte, Birte,Fr?hlich, Roland,Studer, Armido
experimental part, p. 11852 - 11859 (2009/04/07)
The paper describes stereoselective radical aryl migration reactions from sulfur in sulfonates to aryl radicals for the synthesis of axially chiral biaryls. A chirality center in secondary benzylic sulfonates is used to diastereoselectively (atroposelectively) install a stereogenic axis via a 1,5 aryl migration reaction. Atroposelectivity has not been investigated in stereoselective radical chemistry before. Good yields (53-82%) but low selectivities (up to 2 to 1) were obtained.