110210-35-0Relevant academic research and scientific papers
A Ruthenium/Phosphoramidite-Catalyzed Asymmetric Interrupted Metallo-ene Reaction
Trost, Barry M.,Ryan, Michael C.
supporting information, p. 2981 - 2984 (2016/03/19)
Allylic chlorides prepared from commercially available trans-1,4-dichloro-2-butene were converted to trans-disubstituted 5- and 6-membered ring systems with perfect diastereoselectivity and high enantioselectivity under chiral ruthenium catalysis. These products contain stereodefined secondary and tertiary alcohols that originate from the trapping of an alkylruthenium intermediate with adventitious water. Key to the success of this transformation was the development of a new BINOL-based phosphoramidite ligand containing bulky substitution at its 3- and 3′-positions. As a demonstration of product utility, diastereoselective Friedel-Crafts reactions were performed on the chiral benzylic alcohols in high yield and stereoselectivity.
Gold(I)-catalyzed cyclizations of 1,6-enynes: Alkoxycyclizations and exol endo skeletal rearrangements
Nieto-Oberhuber, Cristina,Munoz, M. Paz,Lopez, Salome,Jimenez-Nunez, Eloisa,Nevado, Cristina,Herrero-Gomez, Elena,Raducan, Mihai,Echavarren, Antonio M.
, p. 1677 - 1693 (2007/10/03)
Gold(1) complexes are the most active catalysts for alkoxy- or hydroxycyclization and for skeletal rearrangement reactions of 1,6-enynes. Intramolecular alkoxycyclizations also proceed efficiently in the presence of gold(I) catalysts. The first examples o
Atom Economy. A Simple Pd Catalyzed Addition of Pronucleophiles With Dienes
Trost, Barry M.,Zhi, Lin
, p. 1831 - 1834 (2007/10/02)
Replacing allylic alkylations involving allylic halides, carboxylates, etc. by the simple addition of pronucleophiles to dienes enhances efficiency of use of raw materials and reduces generation of stoichiometric by-products.
SUBSTITUTIONS CATALYSEES AU NICKEL D'ACETATES ET DE SULFONES ALLYLIQUES
Cuvigny, Therese,Julia, Marc
, p. 383 - 408 (2007/10/02)
The allylic substitution of stable enolates derived from diethyl malonate, ethyl cyanoacetate, ethyl benzylsulfonylacetate, bis(benzenesulfonyl)methane and sodium p-toluenesulfinate by a variety of allylic esters and sulfones has been investigated.Suitable ligands and reaction conditions have been found to ensure high yields, and in some cases considerable control of the regioselectivity of the reaction.
