110225-41-7Relevant academic research and scientific papers
Palladium-catalyzed direct 5-arylation of 1,3-dimethyluracil with aryl bromides: An electrophilic metalation-deprotonation with electrophilic arylpalladium intermediate
Kim, Ko Hoon,Lee, Hyun Seung,Kim, Jae Nyoung
scheme or table, p. 6228 - 6233 (2011/12/14)
An efficient method of palladium-catalyzed direct 5-arylation of 1,3-dimethyluracil was developed with a various range of aryl bromides including electron-deficient aryl bromides. 5-Aryluracil derivatives were obtained in moderate to good yields regiosele
Acid-catalyzed photoreaction of 6-chloro-1,3-dimethyl-uracil to p- and m-xylene: formation of novel photo-cycloadducts, 6-methylene-9,11,x-trimethyl-9,11-diazapentacyclo[6.4.0.01,3.0 2,5.04,8]dodecane-10,12-diones and 5-methylene-9,11,x-trimethyl-9,11-diazapentacyclo[6.4.0.01,3.0 2,6.04,8]dodecane-10,12-diones
Ohkura, Kazue,Seki, Koh-Ichi,Hiramatsu, Hajime,Aoe, Keiichi,Terashima, Masanao
, p. 467 - 478 (2007/10/03)
Uv irradiation of 6-chloro-1,3-dimethyluracil in p- and m-xylenes in the presence of trifluoroacetic acid gave novel photocycloadducts, 6-methylene-9,11,x-trimethyl-9,11-diazapentacyclo-[6.4.0.01,3.0 2,5.04,8]dodecane-10,12-diones and 5-methylene-9,11,x-trimethyl-9,11-diazapentacyclo[6.4.0.01,3.0 2,6.04,8]dodecane-10,12-diones, together with tetramethylcyclooctapyrimidine-2,4-diones as the sole regioisomer. The modes of the cycloaddition were discussed.
Photoreaction of 5-Bromo-1,3-dimethyluracil with 1,4-Xylene. The Effect of Acid
Seiki, Koh-ichi,Matsuda, Kohki,Ohkura, Kazue
, p. 175 - 176 (2007/10/02)
The photoreaction of 5-bromo-1,3-dimethyluracil in 1,4-xylene solution yields a mixture of 5- and 6-aryl substituted uracils.The 5-isomer is formed first and is followed by the 6-isomer, the latter being the product from protonated uracil.In the presence of initially added acid (HBr and trifluoroacetic acid) both isomers are formed simultaneously.
PHOTOLYSIS OF 5-BROMO-1,3-DIMETHYLURACIL IN SUBSTITUTED BENZENES
Seki, Koh-ichi,Bando, Yuko,Ohkura, Kazue
, p. 195 - 196 (2007/10/02)
Photolysis of 5-bromo-1,3-dimethyluracyl in toluene, xylene and anisole afforded the anormalously substituted 6-aryl-1,3-dimethyluracils beside the expected products 5-aryl-1,3-dimethyluracils, while the reaction with veratrole occured exclusively at the 5-position of the uracil ring.
