110282-41-2Relevant academic research and scientific papers
Carbapenem antibiotics
-
, (2008/06/13)
Disclosed are novel carbapenem derivatives characterized by a 2-substituent of the formula STR1 in which A represents a C1 -C6 straight or branched chain alkylene group; R5 represents an optionally substituted aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aryl, araliphatic, heteroaryl, heteroaraliphatic, heterocyclyl or heterocyclyl-aliphatic radial and STR2 represents a nitrogen-containing aromatic heterocycle attached to the alkylene group A at a ring carbon atom and quaternized by substituent R5. Such derivatives are useful as potent antibacterial agents.
