110314-31-3

Upstream product

• 110314-30-2 (E)-(3S,4R,5R,7S,11R)-4-Benzyloxy-11-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-propyl]-3,5,7-trimethyl-thiacycloundec-8-en-2-one 
• 110314-27-7 (S)-1-((E)-(2S,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propan-1-ol 
• 110314-26-6 1-((E)-(2R,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propan-1-one 
• 110314-26-6 1-((E)-(2S,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propan-1-one 
• 123488-85-7 [(R)-1-((E)-(2R,6S,8R,9R,10S)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propoxy]-tert-butyl-dimethyl-silane 
• 110314-28-8 [(R)-1-((E)-(2R,6S,8R,9R,10S)-9-Benzyloxy-6,8,10-trimethyl-1-oxo-1λ⁴-thia-cycloundec-4-en-2-yl)-propoxy]-tert-butyl-dimethyl-silane 
• 110314-29-9 {(S)-1-[(E)-(2S,6R,8S,9S,10R)-9-Benzyloxy-11-(diphenyl-phosphinoyl)-6,8,10-trimethyl-thiacycloundec-4-en-2-yl]-propoxy}-tert-butyl-dimethyl-silane 
• 110314-30-2 (E)-(3R,4S,5S,7R,11R)-4-Benzyloxy-11-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-propyl]-3,5,7-trimethyl-thiacycloundec-8-en-2-one 
• 110314-28-8 [(R)-1-((E)-(2R,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-1-oxo-1λ⁴-thia-cycloundec-4-en-2-yl)-propoxy]-tert-butyl-dimethyl-silane 
• 110314-29-9 {(R)-1-[(E)-(2R,6R,8S,9S,10R)-9-Benzyloxy-11-(diphenyl-phosphinoyl)-6,8,10-trimethyl-thiacycloundec-4-en-2-yl]-propoxy}-tert-butyl-dimethyl-silane 
• 110314-27-7 (R)-1-((E)-(2R,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propan-1-ol 
• 123488-85-7 [(R)-1-((E)-(2R,6R,8S,9S,10R)-9-Benzyloxy-6,8,10-trimethyl-thiacycloundec-4-en-2-yl)-propoxy]-tert-butyl-dimethyl-silane 

Downstream Products

• 110314-32-4 (E)-(3S,4R,5R,7S,11S,12R)-4-Benzyloxy-12-ethyl-11-mercapto-3,5,7-trimethyl-oxacyclododec-8-en-2-one 
• 110314-34-6 (E)-(3S,4R,5R,7S,12R)-4-Benzyloxy-12-ethyl-3,5,7-trimethyl-oxacyclododec-8-ene-2,11-dione 
• 110314-33-5 (E)-(3S,4R,5R,7S,11S,12R)-4-Benzyloxy-12-ethyl-3,5,7-trimethyl-11-(2-oxo-2-phenyl-ethylsulfanyl)-oxacyclododec-8-en-2-one 
• 110314-32-4 (E)-(3S,4R,5R,7S,11R,12S)-4-Benzyloxy-12-ethyl-11-mercapto-3,5,7-trimethyl-oxacyclododec-8-en-2-one 
• 110314-36-8 (E)-(3S,4R,5R,7S,8R,12S)-4-Benzyloxy-12-ethyl-8-hydroxy-3,5,7-trimethyl-oxacyclododec-9-ene-2,11-dione 
• 123538-78-3 (E)-(3R,4S,5S,7R,8S,12R)-4-Benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-12-ethyl-3,5,7-trimethyl-oxacyclododec-9-ene-2,11-dione 
• 534-32-7 d,l-Methynolide 
• 534-32-7 d,l-C₁₀-epi-Methynolide 
• 110314-37-9 (E)-(3S,4R,5R,7S,8R,11R,12S)-4-Benzyloxy-12-ethyl-8,11-dihydroxy-3,5,7,11-tetramethyl-oxacyclododec-9-en-2-one 
• 110314-37-9 (E)-(3R,4S,5S,7R,8S,11R,12R)-4-Benzyloxy-12-ethyl-8,11-dihydroxy-3,5,7,11-tetramethyl-oxacyclododec-9-en-2-one 
• 110314-34-6 (E)-(3S,4R,5R,7S,12S)-4-Benzyloxy-12-ethyl-3,5,7-trimethyl-oxacyclododec-8-ene-2,11-dione 
• 110314-38-0 (E)-(3S,4R,5R,7S,11R,12S)-4-Benzyloxy-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-oxacyclododec-9-ene-2,8-dione 
• 110314-38-0 (E)-(3R,4S,5S,7R,11R,12R)-4-Benzyloxy-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-oxacyclododec-9-ene-2,8-dione 
• 110314-35-7 (4R,7R,8S,9S,11R)-8-Benzyloxy-4-ethyl-7,9,11-trimethyl-5,13-dioxa-bicyclo[10.1.0]tridecane-3,6-dione 

Relevant academic research and scientific papers

Total Synthesis of d,l-Methynolide. Sulfur Removal and Remote Stereocontrol

The details for the conversion of 1 into d,l-methynolide are described.Key steps include the highly selective reduction to alcohol 3, the oxidation α to sulfide sulfur from 3 to thiolactone 13, and the acyl transfer from 14 to the lactone 16.Photochemical