11032-79-4 Usage
Description
ALPHA-BUNGAROTOXIN is a protein that binds specifically to acetylcholine receptors. It blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor and prevents the opening of nicotinic receptor-associated ion channels. It is highly specific for the α7-subtype of neuronal nAChR and has a molecular weight of 8000.
Uses
Used in Neurobiological Research:
ALPHA-BUNGAROTOXIN is used as a research tool for studying the function and mechanism of acetylcholine receptors, particularly the α7-subtype. It helps in understanding the role of these receptors in neuronal signaling and synaptic transmission.
Used in Drug Development:
ALPHA-BUNGAROTOXIN can be used in the development of drugs targeting acetylcholine receptors, particularly for conditions related to neuromuscular disorders and cognitive functions. Its high specificity for the α7-subtype makes it a valuable tool in the discovery and optimization of potential therapeutic agents.
Used in Toxicological Studies:
Due to its irreversible binding to acetylcholine receptors, ALPHA-BUNGAROTOXIN can be used in toxicological studies to investigate the effects of neurotoxins on the nervous system and develop potential antidotes or treatments for toxin-induced conditions.
Hazard
Nuerotoxic.
Biochem/physiol Actions
Product does not compete with ATP.
Check Digit Verification of cas no
The CAS Registry Mumber 11032-79-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,3 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 11032-79:
(7*1)+(6*1)+(5*0)+(4*3)+(3*2)+(2*7)+(1*9)=54
54 % 10 = 4
So 11032-79-4 is a valid CAS Registry Number.