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11032-79-4

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11032-79-4 Usage

Chemical Properties

Single polypeptide weight; molecular weight of 8000.

Definition

A protein that binds specifically to acetylcholine receptors.

General Description

Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).

Hazard

Nuerotoxic.

Biochem/physiol Actions

Product does not compete with ATP.

Check Digit Verification of cas no

The CAS Registry Mumber 11032-79-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,3 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 11032-79:
(7*1)+(6*1)+(5*0)+(4*3)+(3*2)+(2*7)+(1*9)=54
54 % 10 = 4
So 11032-79-4 is a valid CAS Registry Number.

11032-79-4Upstream product

11032-79-4Downstream Products

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