110370-69-9

Upstream product

• 141-86-6 2.6-diaminopyridine 
• 1079-66-9 chloro-diphenylphosphine 
• 201230-82-2 carbon monoxide 

Downstream Products

• 137323-07-0 N,N'-bis(diphenylphosphino)-2,6-diaminopyridine-tricarbonyl-manganese iodide water 
• 110305-65-2 {Pt-(N,N'-bis(diphenylphosphino)-2,6-diaminopyridine)-Cl}Cl 
• 110305-63-0 {Ni-(N,N'-bis(diphenylphosphino)-2,6-diaminopyridine)-Cl}Cl*H₂O 
• 850310-61-1 dichloro(2,6-bis(N-diphenylphosphinoamino)pyridine)digold(I) 
• 1433218-99-5 [W(N,N′-bis(diphenylphosphino)-2,6-diaminopyridine)(CO)₃Br]Br 
• 1433219-01-2 [Mo(N,N′-bis(diphenylphosphino)-2,6-diaminopyridine)(CO)₃Br]Br 
• 1476738-26-7 [2,6-Ph2PNHC5H3N(AlClEt2)NPPh2]Cr(μ-Cl)2AlEt2*(toluene) 

Relevant academic research and scientific papers

Structural diversity in Cu(i) complexes of the PNP ligand: From pincer to binuclear coordination modes and their effects upon the electrochemical and photophysical properties

A set of new copper(i) complexes is synthesized and characterized using a labile PNP pincer ligand (PNP = N,N′-bis(diphenylphosphine)-2,6-diaminopyridine). A homoleptic Cu(i) complex [Cu(PNP-κP1:κN1)2]+, (1), was prepared, and taking advantage of the uncoordinated phosphorus atoms in (1), reaction with a second Cu(i) atom bearing secondary ligands (PPh3, phen or dmp) allows the formation of new complexes: a bimetallic helicate [CuI2(PNP)2(phen)]2+, (2), a mononuclear pincer complex [CuI(PNP)(PPh3)]+, (3), and a heteroleptic complex [CuI(PNP)(dmp)]+, (4). All complexes were characterized by X-ray crystallography, NMR (VT-NMR for (1) and (4)), cyclic-voltammetry, and steady-state and time-resolved luminescence spectroscopy. The fluxional behavior in (1) was studied by 31P VT-NMR, where an Ea value of 47.42 kJ mol-1 was calculated for the intramolecular alternating coordination of -PPh2 moieties in PNP to the metal atom. This set of compounds reveals the versatility of the PNP ligand when added to the coordinating properties of Cu(i). The four complexes exhibit emission in solution and complexes (2)-(4) display intense luminescence in the solid state. The oscillographic traces showing the decay of the luminescence were fitted to biexponential functions with time constants: 8.0 μs > τem,1 > 0.37 μs and 50 μs >τem, 2 > 2.2 μs for complexes (2), (3) and (4), respectively. Radiative relaxation is associated with electronic transitions in both the ligand PNP and metal-to-ligand charge transfer (MLCT).

An iron(ii) complex featuring κ3 and labile κ2-bound PNP pincer ligands-striking differences between CH2 and NH spacers

Treatment of anhydrous FeCl2 with 2 equiv. of the pincer ligand PNP-Ph afforded the diamagnetic cationic octahedral complex [Fe(κ3-P,N,P-PNP)(κ2-P,N-PNP)Cl]+ featuring a κ2-P,N-bound PNP ligand. Preliminary reactivity studies revealed that the κ2-P,N-bound PNP ligand is labile reacting with CO to afford trans-[Fe(PNP-Ph)(CO)2Cl]+. This journal is

RETRACTED ARTICLE: Catalytic activity of Fe(II) and Cu(II) PNP pincer complexes for Suzuki coupling reaction

Iron and copper PNP pincer complexes of the type [Fe(L)SO4] and [Cu(L)OCOCH3] are reported and represented as C-1 and C-2 catalyst. Both the complexes were synthesized using bis(diphenylphosphino)pyridine-2,6-diamine [L], and salts of ‘Fe’ and ‘Cu’ by direct coordination method. The as synthesized complexes were characterized using FTIR, UV–Vis, mass analysis and TGA. The effect of reaction time, catalyst load, solvent and base on the reaction between phenylboronic acid and para substituted bromobenzenes in the presence of the catalysts were investigated for evaluating the catalytic efficiency of the complexes. The results obtained highlight the enhanced C-C coupling reactions with the use of 0.4?mol% of the catalyst C-1 in 14?h and 0.6?mol% of C-2 in 16?h respectively with Cs2CO3 base and ACN as solvent media. Of the two complexes reported, C-1 with iron as catalytically active metal is more stable and active towards coupling which is reflected in its better coupling yields in lesser reaction time compared to copper bearing C-2 complex.

Cobalt pincer complex catalyzed Suzuki-Miyaura cross coupling – A green approach

A series of cobalt complexes with tridentate pincer ligands were synthesized to study their catalytic activity in Suzuki-Miyaura coupling reactions. Cobalt complexes, C-1, C-2, C-3 bearing asymmetrical PNCOP pincer ligand [C6H4-1-(NHPPh2)-3-(OPPh2)] (L-1) and symmetrical PNCNP, PNNNP pincer ligands [C6H4-2,6-(NHPPh2)2] (L-2) and [C5H3N-2,6-(NHPPh2)2] (L-3) were synthesized by the reaction of diphenylchlorophosphine with m-aminophenol, m-phenylenediamine and 2,6-diaminopyridine respectively in a 1:2 ratio in the presence of triethylamine as a base and tetrahydrofuran as solvent media. The synthesized complexes were examined for their C-C coupling efficiency in cross-coupling between phenyl boronic acid and para substituted bromobenzenes. Effect of variation of the ligand on the catalytic activity of cobalt pincer complex was explored based on the coupling yields. It is observed that as the number of ‘N’ atoms increases in the side arm of the ligand, the donating ability of the ligand increases which leads to the increased catalytic activity of the complex. The symmetrical PNNNP pincer complex (C-3) was found to be more effective as a catalyst among the complexes synthesized and reported in the present study.

Cobalt-Catalyzed Alkylation of Secondary Alcohols with Primary Alcohols via Borrowing Hydrogen/Hydrogen Autotransfer

Alcohols are promising sustainable starting materials because they can be obtained from abundant and indigestible biomass. The substitution of expensive noble metals in catalysis by earth abundant 3d metals, such as Mn, Fe, or Co, (nonprecious or base metals) is a related key concept with respect to sustainability. Here, we report on the first cobalt-catalyzed alkylation of secondary alcohols with primary alcohols. Easy-to-synthesize and easy-to-activate PN5P-pincer-ligand-stabilized Co complexes developed in our laboratory mediate the reaction most efficiently. The catalysis is applicable to a broad substrate scope and proceeds under relatively mild conditions. We have even demonstrated the coupling of a variety of purely aliphatic alcohols with a base or nonprecious metal catalyst. Mechanistic studies indicate that the reaction follows the borrowing hydrogen or hydrogen autotransfer concept.

General and Mild Cobalt-Catalyzed C-Alkylation of Unactivated Amides and Esters with Alcohols

The borrowing hydrogen or hydrogen autotransfer methodology is an elegant and sustainable or green concept to construct carbon-carbon bonds. In this concept, alcohols, which can be obtained from barely used and indigestible biomass, such as lignocellulose, are employed as alkylating reagents. An especially challenging alkylation is that of unactivated esters and amides. Only noble metal catalysts based on iridium and ruthenium have been used to accomplish these reactions. Herein, we report on the first base metal-catalyzed α-alkylation of unactivated amides and esters by alcohols. Cobalt complexes stabilized with pincer ligands, recently developed in our laboratory, catalyze these reactions very efficiently. The precatalysts can be synthesized easily from commercially available starting materials on a multigram scale and are self-activating under the basic reaction conditions. This Co catalyst class is also able to mediate alkylation reactions of both esters and amides. In addition, we apply the methodology to synthesize ketones and to convert alcohols into aldehydes elongated by two carbon atoms.