110391-10-1

Basic information

• Product Name: (4R,5S,6R)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-2-cyclohexen-1-one
• Synonyms: (4R,5S,6R)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-2-cyclohexen-1-one
• CAS NO: 110391-10-1
• Molecular Weight: 534.652
• Mol File: 110391-10-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (4R,5S,6R)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-2-cyclohexen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,6R)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-2-cyclohexen-1-one(110391-10-1)
• EPA Substance Registry System: (4R,5S,6R)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-2-cyclohexen-1-one(110391-10-1)

Safety Data

• Hazardous Substances Data: 110391-10-1(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 86756-42-5 (4aR,6S,7S,8S,8aR)-7,8-bis(benzyloxy)-2-phenyl-N-((1S,4R,5S,6S)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)cyclohex-2-en-1-yl)hexahydro-4H-benzo[d][1,3]dioxin-6-amine 
• 124330-54-7 (1S,4R,5S,6S)-4,5,6-tris(benzyloxy)-3-((benzyloxy)methyl)-N-((1S,2S,3S,4R,5R)-2,3,4-tris(benzyloxy)-5-((benzyloxy)methyl)cyclohexyl)cyclohex-2-enamine 
• 115250-38-9 (1S)-(1(OH),2,4/1,3)-2,3,4-Tri-O-benzyl-1-C-<(benzyloxy)methyl>-5-oxo-1,2,3,4-cyclohexanetetrol 
• 1413373-15-5 C₃₅H₃₆O₆ 
• 868159-57-3 C₃₅H₄₀O₆ 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 37248-47-8 validamycin A 
• 38665-10-0 (+)-validoxylamine A 
• 114779-32-7 1D-(1,3,6/2)-6-amino-4-benzyloxymethyl-1,2,3-tri-O-benzyltrihydroxycyclohex-4-ene 
• 110372-66-2 1D-(1,2,4,5S/3,5C)-2,3,4-Tri-O-benzyl-5-C-(benzyloxy)methyl-5-C-(ethylthio)-1,2,3,4-cyclohexantetrol 
• 107960-18-9 (2S,3R,4S,5S)-2,3,4-Tris-benzyloxy-5-ethylsulfanyl-5-hydroxymethyl-cyclohexanol 
• 100-44-7 benzyl chloride 
• 13096-62-3 (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one 

Downstream Products

• 1204222-21-8 ((1R,2S,3S,6R)-6-(benzyloxymethyl)-4-(4-chloro-3-((4-cyclopropylphenyl)methyl-d2)phenyl)cyclohex-4-ene-1,2,3-triyl)tris(oxy)tris(methylene)tribenzene 
• 1204221-10-2 (1R,2R,3S,4S,6R)-4-(4-chloro-3-((4-(methoxy-d3)phenyl)methyl-d2)phenyl)-6-(hydroxymethyl)cyclohexane-1,2,3-trioI 
• 1204222-23-0 (1R,2R,3S,4S,6R)-4-(4-chIoro-3-((4-cyclopropylphenyl)methyl-d2)phenyl)-6-(hydroxymethyl)cyclohexane-1,2,3-triol 
• 1413373-77-9 (1R,4R,5S,6R)-4,5,6-tris(benzyloxy)-3-(benzyloxymethyl)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)cyclohex-2-enol 
• 1413373-68-8 C₅₆H₅₈F₂N₂O₆ 
• 1413373-66-6 C₅₆H₅₈N₂O₇ 
• 1413373-64-4 C₅₆H₆₀N₂O₇ 
• 1413373-62-2 C₅₆H₅₈N₂O₆ 
• 1413373-60-0 C₅₃H₅₂N₂O₆ 
• 1413373-54-2 C₁₃H₁₆F₂O₆ 
• 1413373-52-0 C₄₈H₄₆F₂O₆ 
• 1413373-50-8 C₄₈H₄₆O₇ 
• 1413373-48-4 C₄₈H₄₈O₇ 
• 1413373-46-2 C₄₈H₄₆O₆ 

Relevant articles and documents

A hypoglycemic compound and its preparation method and application

The invention discloses an efficient blood glucose reducing compound as well as a preparation and an application thereof. The structure of the compound disclosed by the invention is shown in a formula I, in the formula, R1, R2, R3 and R4 are defined in specification and claims. The invention further discloses the preparation method of the compound shown in the formula I. The compound shown in the formula I has an inhibiting activity to SGLT (Sodium-Glucose-Linked Transporter), and can be effectively used for preventing or treating diseased related to hyperglycemia.

FAMILY OF ARYL, HETEROARYL, O-ARYL AND O-HETEROARYL CARBASUGARS

The present invention relates to a compound of the following formula (I): as well as its process of preparation, pharmaceutical and cosmetics composition comprising it and use thereof, notably as an inhibitor of the sodium-dependent glucose co-transporter, such as SGLTl, SGLT2 and SGLT3, in particular in the treatment or prevention of diabetes, and more particularly type-II diabetes, diabetes-related complications, such as arthritis of the lower extremities, cardiac infarction, renal insufficiency, neuropathy or blindness, hyperglycemia, hyperinsulinemia, obesity, hypertriglyceridemia, X syndrome and arteriosclerosis, as well as for its use as an anticancer, anti-infective, anti-viral, anti-thrombotic or anti- inflammatory drug, or for lightening, bleaching, depigmenting the skin, removing blemishes from the skin, particularly age spots and freckles, or preventing pigmentation of the skin.

BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.