110391-79-2Relevant academic research and scientific papers
Method for selectively preparing hydroquinone monoether compound or quinol compound (by machine translation)
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Paragraph 0040-0045; 0117-0119; 0144-0145, (2020/12/30)
The method comprises the following steps: taking an organic boric acid compound and a p-benzoquinone compound as a reaction raw material, under the action of a copper catalyst, selectively reacting to obtain a hydroquinone monoether compound or a quinol compound. Compared with the prior art, the method disclosed by the invention adopts a one-pot reaction, can selectively obtain two products through solvent control, is suitable for preparing various types of hydroquinone monoether compounds and quinol compounds, and has wide applicability. The substrate functional group is high in tolerance and wide in substrate range. The raw material and the catalyst are cheap and easily available, the reaction conditions are mild, the reaction solvent is green and environment-friendly, the post-treatment is simple, and the yield and purity of the product are high. The preparation method is convenient. The method is rapid and efficient, and has a good application prospect in drug molecule synthesis. (by machine translation)
Structural and Solvent/Electrolyte Effects on the Selectivity and Efficiency of the Anodic Oxidation of Para-Substituted Aromatic Ethers. An Efficient Route to Quinol Ether Ketals and Quinol Ethers
Capparelli, Michael P.,DeSchepper, Richard E.,Swenton, John S.
, p. 4953 - 4961 (2007/10/02)
The anodic oxidations of the methyl ethers of p-arylphenols C6H4, o-C6H4, o-HO2CC6H4>, the 2-hydroxyethyl ethers of p-arylphenols , and the 2-hydroxyethyl ethers of p-alkylphenols and 4-methyl-1-naphthol were studied.The p-aryl aromatic ethers underwent anodic oxidation in good yield to give the corresponding p-quinol ether ketals.The ratio of nuclear to side-chain products from anodic oxidation of p-alkylanisole derivatives is dependent upon the electrolysis conditions.The 2-hydroxyethyl ether derivatives of p-alkylphenols markedly favor the formation of nuclear oxidation products - providing a useful route to the corresponding p-quinol ether ketals.In addition, methanolic potassium fluoride improves the efficiency of these anodic oxidation processes by about 400percent relative to methanolic potassium hydroxide.These reactions were performed at a constant current (1.0-2.0 A) in a single cell and serve as preparative routes to p-quinol ether ketals and quinol ethers via acid hydrolysis.
