110397-99-4

Upstream product

• 110397-96-1 (2S,4R,6R)-6-methoxymethoxy-2,4-dimethylheptyl tosylate 
• 110397-88-1 (2S,4S,6R,8R,1'S)-methyl 2-(1'-hydroxypropyl)-8-methoxymethoxy-4,6-dimethylnonanoate 
• 110397-93-8 (2S,4R,6R)-methoxymethyl 6-methoxymethoxy-2,4-dimethylheptanoate 
• 110397-94-9 (2R,3S,2'S,4'R,6'R)-2-(6'-methoxymethoxy-2',4'-dimethylheptyl)-1,3-pentanediol 
• 110454-83-6 (2S,4R,6R)-methyl 6-hydroxy-2,4-dimethylheptanoix acid 
• 110397-97-2 (2S,4R,6R)-(-)-1-iodo-6-methoxymethoxy-2,4-dimethylheptane 
• 110397-89-2 (2S,4R,6R)-6-methoxymethoxy-2,4-dimethyl-1-heptanol 
• 110397-92-7 N-<(2S,4R,6R)-2,4-dimethyl-6-(3,5-dinitrobenzoyloxy)heptanoyl>-O-(3,5-dinitrobenzoyl)-(S)-prolinol 
• 42558-50-9 methyl (S)-3-hydroxyvalerate 
• 110397-98-3 (2R,4R,6S,7R,8S)-8-mesyloxy-7-mesyloxymethyl-2-methoxymethoxy-4,6-dimethylundecane 

Relevant academic research and scientific papers

SYNTHESIS OF BOTH THE ENANTIOMERS OF LARDOLURE, THE AGGREGATION PHEROMONE OF THE ACARID MITE, LARDOGLYPHUS KONOI

Both the enantiomers of lardolure were synthesized in 100 percent optical purity and 99.6 percent diastereomeric purity by use of Frater's diastereoselective alkylation as the key-step.Since (1R,3R,5R,7R)-enantiomer showed the same ORD sign and bioactivity as those shown by the natural pheromone, the structure of lardolure was established unambiguously as (1R,3R,5R,7R)-1,3,5,7-tetramethyldecyl formate.