110397-99-4Relevant articles and documents
SYNTHESIS OF BOTH THE ENANTIOMERS OF LARDOLURE, THE AGGREGATION PHEROMONE OF THE ACARID MITE, LARDOGLYPHUS KONOI
Mori, Kenji,Kuwahara, Shigefumi
, p. 5539 - 5544 (1986)
Both the enantiomers of lardolure were synthesized in 100 percent optical purity and 99.6 percent diastereomeric purity by use of Frater's diastereoselective alkylation as the key-step.Since (1R,3R,5R,7R)-enantiomer showed the same ORD sign and bioactivity as those shown by the natural pheromone, the structure of lardolure was established unambiguously as (1R,3R,5R,7R)-1,3,5,7-tetramethyldecyl formate.