1104072-55-0

Upstream product

• 1105710-26-6 (R)-tert-butyl 3-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-1-(4-(trifluoromethyl)phenyl)propan-2-ylcarbamate 

Downstream Products

• 1104071-22-8 C₁₇H₂₄F₃N₃O₃ 
• 1104071-21-7 (R)-4-(tertbutoxycarbonylamino)-5-(4-(trifluoromethyl)phenyl)pentanoic acid 
• 1236031-45-0 (R)-tert-butyl 5-amino-5-oxo-1-(4-(trifluoromethyl)phenyl)pentan-2-ylcarbamate 

Relevant academic research and scientific papers

FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE

The invention relates to thiazole compounds of Formula (I) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

HETEROCYCLIC MODULATORS OF PKB

The invention relates to heterocyclic compounds of Formula I and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein Formula (I). The invention also relates to the therapeutic use of such compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.