110414-77-2 Usage
General Description
Gelsemiol is a toxic alkaloid found in plants of the Gelsemium genus, including Gelsemium sempervirens, also known as yellow jasmine or wild woodbine. It is a highly potent neurotoxin that can cause paralysis and respiratory failure in humans and animals when ingested. Gelsemiol acts as a competitive antagonist of the gamma-aminobutyric acid (GABA) receptor, leading to inhibition of nerve impulses and muscle relaxation. Due to its toxicity, gelsemiol has been used historically as a poison for criminal purposes, but it also has potential applications in medicine, particularly in the field of anesthesiology. However, its use is highly restricted and regulated due to its extreme toxic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 110414-77-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,4,1 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 110414-77:
(8*1)+(7*1)+(6*0)+(5*4)+(4*1)+(3*4)+(2*7)+(1*7)=72
72 % 10 = 2
So 110414-77-2 is a valid CAS Registry Number.
110414-77-2Relevant articles and documents
Total synthesis of gelsemiol
Burch, Patrick,Binaghi, Massimo,Scherer, Manuel,Wentzel, Corinna,Bossert, David,Eberhardt, Luc,Neuburger, Markus,Scheiffele, Peter,Gademann, Karl
supporting information, p. 2589 - 2591 (2013/03/14)
Let it grow! The neuritogenic iridoid gelsemiol has been prepared in synthetic form by a radical cascade and skeletal rearrangement. This compound accelerates the differentiation of neurons and growth of neuritis (see scheme). Copyright
