1104455-83-5Relevant academic research and scientific papers
Molecular addition compounds. 10. Borane adducts with N,N-dialkylanilines for hydroboration
Brown, Herbert C.,Zaidlewicz, Marek,Dalvi, Pramod V.
, p. 4202 - 4205 (1998)
Borane adducts with selected N,N-dialkylanilines have been prepared and examined as hydroborating agents. The adduct H3B:NPhPri2 is a solid, considered less desirable than liquid adducts as hydroborating agents. Fortunately, the adducts H3B:NPhBuiMe, H3B: NPhPriMe, H3B:NPhPriEt, and H3B:NPhPriPrn are liquids above 0 °C, hydroborating 1-octene in tetrahydrofuran in less than 1 h at room temperature. Convenient procedures are described for generating gaseous diborane quantitatively, either by thermal dissociation of the borane-N,N-diisopropylaniline adduct or by the reaction of a 2.00 M solution of sodium borohydride in triglyme with a 5.40 M solution of boron trifluoride in triglyme.
Iron-Catalyzed Oxyalkylation of Terminal Alkynes with Alkyl Iodides
Deng, Weili,Ye, Changqing,Li, Yajun,Li, Daliang,Bao, Hongli
supporting information, p. 261 - 265 (2019/01/10)
A general oxyalkylation of terminal alkynes enabled by iron catalysis has been developed. Primary and secondary alkyl iodides acted as the alkylating reagents and afforded a range of α-alkylated ketones under mild reaction conditions. Acetyl tert-butyl peroxide (TBPA) was used as the radical relay precursor, providing the initiated methyl radical to start the radical relay process. Preliminary mechanistic studies were conducted, and late-stage functionalizations of natural product derivatives were performed.
