1104490-97-2Relevant academic research and scientific papers
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors
Shen, Hong C.,Ding, Fa-Xiang,Deng, Qiaolin,Xu, Suoyu,Chen, Hsuan-shen,Tong, Xinchun,Tong, Vincent,Zhang, Xiaoping,Chen, Yuli,Zhou, Gaochao,Pai, Lee-Yuh,Alonso-Galicia, Magdalena,Zhang, Bei,Roy, Sophie,Tata, James R.,Berger, Joel P.,Colletti, Steven L.
supporting information; scheme or table, p. 5314 - 5320 (2010/07/03)
3,3-Disubstituted piperidine-derived trisubstituted urea entA-2b was discovered as a highly potent and selective soluble epoxide hydrolase (sEH) inhibitor. Despite the good compound oral exposure, excellent sEH inhibition in whole blood, and remarkable se
