110457-27-7

Upstream product

• 25145-43-1 2-phenylpropionyl chloride 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 

Downstream Products

• 110457-30-2 (S)-2-hydroxymethyl-N-((S)-2-hydroxy-2-phenyl)propanoylpyrrolidine 
• 110457-29-9 (S)-2-hydroxymethyl-N-((R)-2-hydroxy-2-phenyl)propanoylpyrrolidine 

Relevant academic research and scientific papers

Asymmetric Oxidation of Chiral Enolates in the Preparation of Acyclic Tertiary α-Hydroxy Amides in High Optical Purity

Asymmetric oxidation of chiral acyclic, tetrasubstituted enolate 4c with oxaziridines (+)-1/(-)-2 in the presence and absence of HMPA affords optically active tertiary α-hydroxy amide 5c in high optical purity (88-91percent de).The application of (+)-1/(-)-2 as "chiral probes" of enolate-electrophile reaction mechanisms is proposed.