1104638-98-3Relevant academic research and scientific papers
Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidines
Cikotiene, Inga,Kairys, Visvaldas,Buksnaitiene, Rita,Morkunas, Marius,Rudys, Simonas,Brukstus, Algirdas,Fernandes, Miguel X.
, p. 5752 - 5759 (2009)
Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines has been developed. The i
An efficient one-pot synthetic method for 2,4-disubstituted 7-arylpyrido [4,3-d]pyrimidines from 2,4-disubstituted 6-(arylethynyl)pyrimidine-5- carbaldehydes and tert-butylamine
Cikotiene, Inga,Morkunas, Marius,Rudys, Simonas,Buksnaitiene, Rita,Brukstus, Algirdas
experimental part, p. 2799 - 2802 (2009/05/07)
Unexpected thermal cyclization of 2,4-disubstituted 6-(arylethynyl) pyrimidine-5-carbaldehydes with tert-butylamine proceeded to give 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines in good yields in the absence of any catalysts. The intermediate compoun
