1104643-25-5 Usage
Uses
Used in Pharmaceutical Industry:
(S)-4-tert-butoxypyrrolidine is used as a chiral building block for the synthesis of various drugs, leveraging its unique stereochemistry to create enantiomerically pure compounds, which is crucial for the development of effective and safe medications.
Used in Organic Synthesis:
(S)-4-tert-butoxypyrrolidine is used as a key intermediate in the synthesis of complex organic molecules, facilitating the construction of specific molecular frameworks and enhancing the overall efficiency of the synthesis process.
Used in Catalysis and Asymmetric Synthesis:
(S)-4-tert-butoxypyrrolidine is used as a ligand in metal-catalyzed asymmetric reactions, enabling the selective formation of enantiomerically pure products. This application is vital for the production of chiral compounds with desired biological activities and reducing the formation of unwanted enantiomers.
Check Digit Verification of cas no
The CAS Registry Mumber 1104643-25-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,4,6,4 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1104643-25:
(9*1)+(8*1)+(7*0)+(6*4)+(5*6)+(4*4)+(3*3)+(2*2)+(1*5)=105
105 % 10 = 5
So 1104643-25-5 is a valid CAS Registry Number.
1104643-25-5Relevant articles and documents
PROCESS FOR THE EFFICIENT PREPARATION OF 3-HYDROXY PYRROLIDINE AND DERIVATIVES THEREOF
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Page/Page column 15, (2009/03/07)
The present invention relates to an effective process for the preparation of 3-hydroxypyrrolidine or derivatives thereof. The process comprises (a) protecting a hydroxyl group of 4-halo-3-hydroxybutyric acid, (b) reducing an ester group of the compound obtained from the step (a) to obtain a corresponding alcohol compound, (c) reacting the compound obtained from the step (b) with sulfonyl halide to produce a corresponding sulfonate compound, (d) reacting the compound obtained from the step (c) with an amine to obtain 3-hydroxy-protected pyrrolidine compound, and (e) deprotecting the compound obtained from the step (d) to produce the targeted 3-hydroxypyrrolidine or derivatives thereof. The process provides 3-hydroxypyrrolidine or derivatives thereof with high optical purity, because optical purity of the starting material is substantially retained. In the process, each of the steps is carried out in a mild condition and does not require any special purification. This means that the process is useful and adequate for industrial mass production of 3-hydroxypyrrolidine and derivatives thereof having high optical purity.
