1104733-34-7Relevant academic research and scientific papers
Stability of medium-bridged twisted amides in aqueous solutions
Szostak, Michal,Yao, Lei,Aube, Jeffrey
, p. 1869 - 1875 (2009)
"Twisted" amides containing nonstandard dihedral angles are typically hypersensitive to hydrolysis, a feature that has stringently limited their utility in water. We have synthesized a series of bridged lactams that contain a twisted amide linkage but exh
Cation-n control of regiochemistry of intramolecular schmidt reactions en route to bridged bicyclic lactams
Szostak, Michal,Yao, Lei,Aube, Jeffrey
supporting information; experimental part, p. 4386 - 4389 (2009/12/26)
The regiochemistry of the intramolecular Schmidt reaction of 2-azidoalkylketones is controlled by placing a thioether substituent at the position adjacent to the ketone to provide access to a family of unsubstituted medium bridged twisted amides. This out
