110477-25-3

Upstream product

• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 105222-94-4 C₉H₁₇BrMgSi 
• 112129-48-3 1-bromo-6-(trimethylsilyl)-4-hexyne 
• 76711-41-6 1-(Trimethylsilyl)-2-hexyn-6-ol 
• 13361-64-3 trimethyl(propargyl)silane 
• 108207-95-0 (trimethylsilyl)-1 (tetrahydropyrannyl-2 oxy)-6 hexyne-2 

Relevant academic research and scientific papers

Intramolecular Cyclization of Allyl- and Propargylsilanes. The Regio- and Stereochemical Outcome of the Cyclization

The syntheses of allyl- and propargylsilanes and their additions to enones and dienones are described.Propargylsilanes of type 1 undergo cyclization to spirodecanes with EtAlCl2 or TiCl4 as the Lewis acid catalyst.Propargylsilanes of type 2 cyclize upon treatment with EtAlCl2 to fused nonanes.Allylsilanes of type 15 undergo regioselective 1,6-additions to dienones to form bicycloundecenones 21, and propargylsilanes of type 14 cyclize regioselectively in 1,4 fashion (bicyclononanones).Allylsilane 16 forms either a bicyclododecenone (with TiCl4) or a 1:1 mixture of the latter compound and a bicyclodecanone (with EtAlCl2).

INTRAMOLECULAR CYCLIZATIONS OF ALLYL- AND PROPARGYLSILANES

Allylsilanes of type 5 and propargylsilanes of type 13 undergo efficient cyclizations upon treatment with EtAlCl2 in toluene to afford stereoselectively functionalized hydrindanones of type 6 and spirodecanes of type 14.