110522-46-8

Upstream product

• 94898-52-9 2,3,5-tri-O-benzyl-α-D-arabinofuranosyl fluoride 
• 10457-14-4 O,O'-bis-(trimethylsilyl)uracil 
• 153481-95-9 (2R,3R,4S)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-phenylsulfanyl-tetrahydro-furan 

Relevant academic research and scientific papers

Stereoselective Synthesis of 1,2-cis-N-Glycosides by the N-Bromosuccinimide Promoted Reaction of Thioglycosides with Silylated Pyrimidine Bases

The coupling of O-benzylated 1-thioglycosides, derived from D-glucose, D-mannose, D-ribose, D-xylose, and D-arabinose, with silylated pyrimidine bases by activation with N-bromosuccinimide uniformly afforded the corresponding 1,2-cis-N-glycosides with good selectivity.

Condensation of 1-Fluorofuranones and Silylated Nucleobases Catalyzed by Tetrafluorosilane

The title reaction provides a generally useful tool for nucleoside synthesis.The stereoselectivities are highly influenced by the fluoride substrates, and steric course of the reaction of O-benzylated ribofuranosyl fluoride is solvent dependent.