110525-53-6

Basic information

• Product Name: 4-(2-METHYLIMIDAZOL-1-YL)BUTYRIC ACID ETHYL ESTER
• Synonyms: 4-(2-METHYLIMIDAZOL-1-YL)BUTYRIC ACID ETHYL ESTER
• CAS NO: 110525-53-6
• Molecular Formula: C10H16N2O2
• Molecular Weight: 196.24624
• Mol File: 110525-53-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 334.3°Cat760mmHg
• Flash Point: 156°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.000129mmHg at 25°C
• Refractive Index: 1.513
• PKA: 7.72±0.31(Predicted)
• CAS DataBase Reference: 4-(2-METHYLIMIDAZOL-1-YL)BUTYRIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-METHYLIMIDAZOL-1-YL)BUTYRIC ACID ETHYL ESTER(110525-53-6)
• EPA Substance Registry System: 4-(2-METHYLIMIDAZOL-1-YL)BUTYRIC ACID ETHYL ESTER(110525-53-6)

Safety Data

• Hazardous Substances Data: 110525-53-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H16N2O2/c1-3-14-10(13)5-4-7-12-8-6-11-9(12)2/h6,8H,3-5,7H2,1-2H3

Upstream product

• 693-98-1 2-methylimidazole 
• 2969-81-5 Ethyl 4-bromobutyrate 

Relevant articles and documents

Synthesis and biological evaluation of novel 99mtc-labelled bisphosphonates as superior bone imaging agents

A series of novel zoledronic acid (ZL) derivatives 1-hydroxy-3-(2-methyl- 1H-imidazol-1-yl)propane-1,1-diyldiphosphonic acid (MIPrDP), 1-hydroxy-4-(2-methyl-1H-imidazol-1-yl)butane-1,1-diyldiphosphonic acid (MIBDP), and 1-hydroxy-5-(2-methyl-1H-imidazol-1-yl)pentane-1,1-diyldiphosphonic acid (MIPeDP) were prepared and successfully labeled with 99mTc in high labeling yields. The in vitro stability and in vivo biodistribution of 99mTc-MIPrDP, 99mTc-MIBDP and 99mTc-MIPeDP were investigated and compared. The biodistribution studies indicate that the radiotracer 99mTc-MIPrDP has highly selective uptake in the skeletal system and rapid clearance from soft tissues. The present findings indicate that 99mTc-MIPrDP holds great potential for use in bone imaging.