110525-59-2

Upstream product

• 288-32-4 1H-imidazole 
• 103564-55-2 5-chloro-5-nitro-2-phenyl-[1,3]dioxane 
• 58522-87-5 5-bromo-5-nitro-2-phenyl-1,3-dioxane 

Downstream Products

• 117377-13-6 1-(5-Isopropyl-2-phenyl-[1,3]dioxan-5-yl)-1H-imidazole 
• 117377-06-7 1-[5-(1-Methyl-1-nitro-ethyl)-2-phenyl-[1,3]dioxan-5-yl]-1H-imidazole 
• 117377-07-8 1-(5'-Nitro-2,2'-diphenyl-[5,5']bi[[1,3]dioxanyl]-5-yl)-1H-imidazole 
• 117377-04-5 1-{5-[1-Methyl-1-nitro-2-(tetrahydro-pyran-2-yloxy)-ethyl]-2-phenyl-[1,3]dioxan-5-yl}-1H-imidazole 
• 117377-04-5 1-{5-[1-Methyl-1-nitro-2-(tetrahydro-pyran-2-yloxy)-ethyl]-2-phenyl-[1,3]dioxan-5-yl}-1H-imidazole 
• 117377-04-5 1-{5-[1-Methyl-1-nitro-2-(tetrahydro-pyran-2-yloxy)-ethyl]-2-phenyl-[1,3]dioxan-5-yl}-1H-imidazole 
• 117377-14-7 1-{5-[1-Methyl-2-(tetrahydro-pyran-2-yloxy)-ethyl]-2-phenyl-[1,3]dioxan-5-yl}-1H-imidazole 

Relevant academic research and scientific papers

REACTIVITE SRN1 D'(α-NITROALKYL)-1 IMIDAZOLES: SYNTHESE D'IMIDAZOLES ALCOYLES EN POSITION 1 PAR DES CHAINES RAMIFIEES ET FONCTIONNALISEES.

Gem-nitro imidazolyl alkanes reacting under SRN1 conditions undergo nitro group replacement by variously substituted nitronates to give imidazoles carrying on position 1 tertiary alkyl chain R1R2-C-CNO2(R3R

SUBSTITUTION NUCLEOPHYLE RADICALAIRE EN CHAINE (SRN1). 16eme MEMOIRE: N-ALCOYLATION DE L'IMIDAZOLE, DU BENZIMIDAZOLE, DU PYRRAZOLE ET DU TRIAZOLE

The title amines behave as nucleophiles towards p-nitrobenzylchloride or variously funtionnalyzed gem-halo nitro alkanes in reactions responding to the classical criteria for the SRN1 mechanism.