110527-67-8 Usage
Uses
Used in Pharmaceutical Synthesis:
(S)-2-(((Benzyloxy)carbonyl)amino)-3-((S)-2-oxoindolin-3-yl)propanoic acid is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, potentially leading to the development of new drugs with specific therapeutic properties.
Used in Biochemical Research:
In the field of biochemical research, (S)-2-(((benzyloxy)carbonyl)amino)-3-((S)-2-oxoindolin-3-yl)propanoic acid is used as a key component in the study of molecular interactions and the development of novel biochemical compounds. Its chiral nature and unique structural features make it a promising candidate for investigating biological processes and creating targeted therapies.
Used in Drug Design:
(S)-2-(((Benzyloxy)carbonyl)amino)-3-((S)-2-oxoindolin-3-yl)propanoic acid is utilized in drug design for its potential to be modified and optimized for specific pharmacological activities. Its incorporation into larger molecular frameworks can lead to the creation of drugs with enhanced efficacy, selectivity, and reduced side effects.
Used in Chiral Chemistry:
In chiral chemistry, (S)-2-(((benzyloxy)carbonyl)amino)-3-((S)-2-oxoindolin-3-yl)propanoic acid is used as a building block for the creation of enantiomerically pure compounds. (S)-2-(((benzyloxy)carbonyl)amino)-3-((S)-2-oxoindolin-3-yl)propanoic acid's (S) configuration at both key positions allows for the development of chiral molecules with specific biological activities, which is crucial in the pharmaceutical industry where the stereochemistry of a drug can significantly impact its efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 110527-67-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,5,2 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 110527-67:
(8*1)+(7*1)+(6*0)+(5*5)+(4*2)+(3*7)+(2*6)+(1*7)=88
88 % 10 = 8
So 110527-67-8 is a valid CAS Registry Number.
110527-67-8Relevant academic research and scientific papers
A concise preparation of the non-proteinogenic amino acid l-kynurenine
Kleijn, Laurens H.J.,Müskens, Frederike M.,Oppedijk, Sabine F.,De Bruin, Gerjan,Martin, Nathaniel I.
supporting information, p. 6430 - 6432 (2013/01/15)
A concise and practical preparation of the non-proteinogenic amino acid l-kynurenine is reported. The synthetic approach is scalable and provides ready access to this valuable amino acid in either l- or d-stereochemistry starting from l- or d-tryptophan, respectively. In the optimized procedure, two discreet oxidation steps are applied sequentially to convert the tryptophan indole ring into the keto-aniline moiety contained within the kynurenine side chain.
COMPOUNDS USEFUL AS MODULATORS OF THE PROTEASOME ACTIVITY
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Page/Page column 38, (2008/06/13)
The present invention relates to the use of compounds of the following general formula (I): wherein no is 0 or 1, and when no is 1, X = CH2 or X = NCH2C6H5; R1 is OH, or a OR10 group, or a group of formula NH-(CH2)n1-R11; R2 is H, or an alkyl group, or a group of formula (CH2)n2-(CO)n3-NR13R14; R3 is H, or an alkyl group; R4 is H, or Boc, or Z; R5 is H, or Boc, or Z ; R6 is a OR16 group; R7 and R8 are H, or a halogen atom, as modulators of the proteasome activity, in the frame of the preparation of a medicament useful for the prevention or treatment of diseases wherein the proteasome is involved, or the preparation of cosmetic compositions, or of phytosanitary compositions.
