110535-85-8Relevant academic research and scientific papers
Copper-catalyzed C-N coupling reaction of tosylhydrazones
Wu, Xufeng,Li, Lingyu,Jiang, Wenlong,Zhou, Lihong,Zeng, Qingle
, (2018/08/01)
Tosylhydrazones are a kind of labile and highly reactive compounds, which are apt to be transformed into reactive diazo compounds and then into extremely reactive carbenes under the basic condition. In order to fulfil the valuable C-N coupling reaction, diaryliodonium salts are evaluated and prove to be a class of efficient electrophiles. The reaction with ligand-free copper salt as catalyst shows a wide range of substrate scope. A plausible mechanism is proposed.
Synthesis of 3-substituted indazoles from arynes and N-tosylhydrazones
Li, Pan,Zhao, Jingjing,Wu, Chunrui,Larock, Richard C.,Shi, Feng
body text, p. 3340 - 3343 (2011/09/12)
Readily available, stable, and inexpensive N-tosylhydrazones react with arynes under mild reaction conditions to afford 3-substituted indazoles in moderate to good yields. The reaction appears to involve a dipolar cycloaddition of in situ generated diazo
