110549-03-6

Basic information

• Product Name: (7aS,13aS)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
• Synonyms: 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aS-cis)-
• CAS NO: 110549-03-6
• Molecular Formula: C₂₃H₂₂O₇
• Molecular Weight: 410.4166
• Mol File: 110549-03-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 623.4°C at 760 mmHg
• Flash Point: 219.3°C
• Density: 1.341g/cm³
• Vapor Pressure: 2.11E-16mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: (7aS,13aS)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (7aS,13aS)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one(110549-03-6)
• EPA Substance Registry System: (7aS,13aS)-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one(110549-03-6)

Safety Data

• Hazardous Substances Data: 110549-03-6(Hazardous Substances Data)

Upstream product

• 372-20-3 3-fluorophenol 
• 185913-28-4 2-(3-fluorophenoxy)tetrahydro-2H-pyran 
• 522-17-8 (-)-deguelin 
• 54013-49-9 2,3-dihydro-6,7-dimethoxy-4H-1-benzopyran-4-one 
• 522-17-8 cis-deguelin 

Relevant articles and documents

General Synthetic Approach to Rotenoids via Stereospecific, Group-Selective 1,2-Rearrangement and Dual S N Ar Cyclizations of Aryl Fluorides

A general synthetic approach to rotenoids is described, featuring 1) stereospecific, group-selective 1,2-rearrangements of epoxy alcohols, and 2) S N Ar oxy-cyclizations of aryl fluorides. The common intermediate epoxyketone, en route to (-)-rotenone and (-)-deguelin, was prepared from d -araboascorbic acid in five steps. Also described is the conversion of (-)-deguelin into oxidized congeners, (-)-tephrosin and (+)-12a- epi -tephrosin.