110577-68-9

Upstream product

• 64-17-5 ethanol 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 594-19-4 tert.-butyl lithium 
• 69341-75-9 N,N-dimethylfluoroamide-di-tert-butyl acetate 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 110577-57-6 1-<2-(4-chlorobenzyl)-3,3-dimethylbutanoyl>imidazole 
• 107021-84-1 2-(4-Chloro-benzyl)-3,3-dimethyl-1-[1,2,4]triazol-1-yl-butan-1-one 
• 110577-61-2 2-(4-chlorobenzyl)-3,3-dimethylbutanoyl chloride 

Relevant academic research and scientific papers

On the mechanism of the addition of organolithium reagents to cinnamic acids

The regioselectivity of the addition of tert-butyllithium to cinnamic acid is subject to reaction conditions and to substituent electronic effects. Significant effects are observed in the presence of several additives including a radical trap such as α-methylstyrene. Competition experiments by addition of the organolithium reagent to mixtures of substituted cinnamic acids show that the relative rates of both conversion of the starting acids and formation of the 1,3-adducts are subject to electronic effects, whereas rates for 1,4-addition are independent of the substituents. These features are in agreement with a polar addition mechanism, but a fast SET equilibrium followed by slow radical combination would be possible as well.

Structure-Activity Relationships in Fungicidal 1-(2-Benzyl-3,3-dimethylbutanoyl)imidazoles and Related Compounds

1-(2-Benzyl-3,3-dimethylbutanoyl)imidazoles and related compounds were prepared and tested for their fungicidal activity against powdery mildew on barley (Erysiphe graminis) and gray mold on cucumber (Botrytis cinerea) by pot tests.The benzyl group at the