110589-54-3

Upstream product

• 1016-77-9 3-bromobenzophenone 
• 1666-13-3 diphenyl diselenide 

Relevant academic research and scientific papers

ELECTROCHEMICAL SYNTHESIS OF SELENO AND TELLURO DERIVATIVES IN MeCN

Large-scale electrolysis with concurrent sonication in MeCN allows for the synthesis of a large variety of seleno and telluro derivatives.Aliphatic chalcogenides REER or RER (E = Se, Te) can be prepared by reduction of E powder to E2(2-) or E(2-), followed by addition of an alkyl halide RX.Depending upon R, substitution can compete with homogeneous electron or H+ transfers.RE+ can be prepared by anodic oxidation of REER, and trapped by nucleophiles and olefins.The synthesis of aromatic chalcogenides ArEAr'can be carried out by electrochemically inducedSRN1 substitution.The yields are improved by redox catalysis.Under such conditions, the synthesis of PhEAr (Ar = NCC6H4, PhCOC6H4) proceeds in good yields.ArEEAr and ArEAr can be prepared by cathodic reduction of PhEAr.

Electrochemical Synthesis of (Phenylseleno)benzophenones and (Phenyltelluro)benzophenones by the SRN1 Mechanism, Using a Redox Catalyst

Benzophenone derivatives substituted by o-, m-, or p-phenyltelluro and m- or p-phenylseleno groups have been synthesised in acetonitrile by the mediated cathodic reduction of bromobenzophenone in the presence of an equivalent amount of PhTe- or PhSe- initially prepared by electrochemical reduction of the corresponding diphenyl dichalcogenide.Azobenzene (0.1 equiv) was utilized as redox catalyst.Sonication was maintained during electrolysis and an acid such as fluorene or malononitrile(0.5 equiv) was present to avoid the formation of -CH2CN and its addition upon the bromo or chalcogeno ketones.Under such conditions, the chalcogeno ketones were isolated in 44-86percent yields.In the case of the m- and p-telluro ketones whose yields are moderate (48percent and 44percent), the formation of (PhCOC6H4)2Te proceeded simultaneously (31percent and 36percent).