110597-47-2

Upstream product

• 6702-55-2 3,4-dihydroxy-2-methoxyxanthone 
• 100-44-7 benzyl chloride 
• 33018-29-0 4-formyl-3-hydroxy-2-methoxyxanthone 
• 126365-59-1 4-formyl-3-benzyloxy-2-methoxyxanthone 

Downstream Products

• 110597-48-3 ethyl 2-<9H-(3-benzyloxy-2-methoxy-9-oxo)xanthen-4-yl>oxy-3-oxo-3-(4-benzyloxy-3-methoxyphenyl)propionate 
• 110597-49-4 ethyl 2-<9H-(3-hydroxy-2-methoxy-9-oxo)xanthen-4-yl>oxy-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionate 
• 110597-51-8 2,3-dihydro-2-ethoxycarbonyl-3-(4-hydroxy-3-methoxyphenyl)-5-methoxy-7H-1,4-dioxino-<2,3-c>xanthen-7-one 
• 64280-48-4 (+/-)-cis-kielcorin 
• 126365-64-8 erythro-1,3-diacetoxy-1-(4-acetoxy-3-methoxyphenyl)-2-<3-acetoxy-2-methoxy-9-oxo-4-xanthenyloxy>propane 
• 126365-64-8 threo-1,3-diacetoxy-1-(4-acetoxy-3-methylphenyl)-2-<3-acetoxy-2-methoxy-9-oxo-4-xanthenyloxy>propane 
• 64280-51-9 diacetylkielcorin 
• 126365-61-5 ethyl 2-<3-hydroxy-2-methoxy-9-oxo-4-xanthenyloxy>-3-(4-hydroxy-3-methoxyphenyl)-3-oxopropionate 
• 70522-37-1 1-(hydroxy-3-methoxyphenyl)-2-<3-hydroxy-2-methoxy-9-oxo-4-xanthenyloxy>propane-1,3-diol 
• 64280-48-4 (+/-)-kielcorin 

Relevant academic research and scientific papers

Total Synthesis of a Xanthonolignoid, Kielcorin

The reaction of 3-benzyloxy-4-hydroxy-2-methoxyxanthone with ethyl 2-bromo-3-(4-benzyloxy-3-methoxyphenyl)-3-oxopropionate in the presence of potassium tert-butoxide afforded the condensation product (8) which was converted to the debenzylation product (9

Synthesis of Kielcorin

The synthesis of kielcorin, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-hydroxymethyl-5-methoxy-7H-1,4-dioxinoxanthen-7-one (13) and desmethoxykielcorin (12), a model compound have been accomplished.The intermediate ethyl O-benzylvanilloyl bromoace