110623-52-4Relevant academic research and scientific papers
3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants
-
, (2008/06/13)
This invention relates to the treatment of depression by administration of novel 3-(Rn -phenyl)-1,4-dialkyl-1,2,4-triazolium salts of the formula STR1 wherein R is halogen, trifluoromethyl, C1-4 lower alkyl or C1-4 lower alkoxy, n is zero, 1 or 2, and R1 and R4 independently represent C1-3 lower alkyl; and A- represents a pharmaceutically acceptable anion.
An improved method for the synthesis of 5-aryl-3-methyl-2-methylimino-1,3,4-oxadiazoles
Kane,Staeger
, p. 1 - 11 (2007/10/02)
5-Aryl-3-methyl-2-methylimino-1,3,4-oxadiazoles were prepared in 54-81% yields by the mercuric oxide-induced cyclizations of 1-aroyl-2,4,-dimethylthiosemicarbazides.
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as Potential Antidepressant Agents
Kane, John M.,Dudley, Mark W.,Sorensen, Stephen M.,Miller, Francis P.
, p. 1253 - 1258 (2007/10/02)
A series of 5-aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones was prepared and evaluated for potential antidepressant activity.Members of this series were generally prepared by the alkaline ring closures of the corresponding 1-aroylthiosemicarbazides.Several
