Gastric Inhibitory Polypeptide (GIP), also known as the glucose-dependent insulinotropic polypeptide, is a hormone that plays a critical role in the regulation of insulin secretion, blood sugar levels, and nutrient absorption in the body. It is primarily produced in the K cells of the duodenum and jejunum in response to nutrient ingestion. The porcine version refers to the GIP derived from pigs, which is often used in scientific research due to its physiological and structural similarities to human GIP. This hormone not only stimulates insulin secretion, but also influences various aspects of digestion and absorption, making it a crucial player in metabolic regulation.
11063-17-5
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Basic information
- Product Name: GASTRIC INHIBITORY POLYPEPTIDE (PORCINE)
- Synonyms: YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHNITQ;H-TYR-ALA-GLU-GLY-THR-PHE-ILE-SER-ASP-TYR-SER-ILE-ALA-MET-ASP-LYS-ILE-ARG-GLN-GLN-ASP-PHE-VAL-ASN-TRP-LEU-LEU-ALA-GLN-LYS-GLY-LYS-LYS-SER-ASP-TRP-LYS-HIS-ASN-ILE-THR-GLN-OH;GASTRIC INHIBITORY PEPTIDE, PORCINE;GASTRIC INHIBITORY PEPTIDE, PORCINE (1-42);GASTRIC INHIBITORY POLYPEPTIDE (PORCINE);GIP;GIP (PORCINE);GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (PORCINE)
- CAS NO:11063-17-5
- Molecular Formula: C225H342N60O66S1
- Molecular Weight: 4975.55
- EINECS: N/A
- Product Categories: peptide
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: GASTRIC INHIBITORY POLYPEPTIDE (PORCINE)(CAS DataBase Reference)
- NIST Chemistry Reference: GASTRIC INHIBITORY POLYPEPTIDE (PORCINE)(11063-17-5)
- EPA Substance Registry System: GASTRIC INHIBITORY POLYPEPTIDE (PORCINE)(11063-17-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 11063-17-5(Hazardous Substances Data)
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11063-17-5 Usage
Uses
Used in Scientific Research:Gastric Inhibitory Polypeptide (Porcine) is used as a research tool for understanding the mechanisms of insulin secretion, blood sugar regulation, and nutrient absorption. Its structural and physiological similarities to human GIP make it an ideal model for studying the role of GIP in metabolic regulation.
Used in Pharmaceutical Development:
Gastric Inhibitory Polypeptide (Porcine) is used as a potential therapeutic agent for the treatment of diabetes and other metabolic disorders. Its ability to stimulate insulin secretion and influence nutrient absorption makes it a promising candidate for developing new drugs that can improve glucose homeostasis and overall metabolic health.
Used in Nutritional Studies:
Gastric Inhibitory Polypeptide (Porcine) is used as a biomarker in nutritional studies to assess the impact of different dietary components on insulin secretion and glucose metabolism. This can help in the development of personalized dietary recommendations and interventions for individuals with metabolic disorders.
Used in Diagnostic Applications:
Gastric Inhibitory Polypeptide (Porcine) is used as a diagnostic marker for identifying individuals with impaired insulin secretion or other metabolic abnormalities. Measuring GIP levels can provide valuable insights into the underlying causes of these conditions and guide appropriate treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 11063-17-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,6 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.Calculate Digit Verification of CAS Registry Number 11063-17:
(7*1)+(6*1)+(5*0)+(4*6)+(3*3)+(2*1)+(1*7)=55
55 % 10 = 5
So 11063-17-5 is a valid CAS Registry Number.
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GASTRIC INHIBITORY POLYPEPTIDE (PORCINE)
