1106736-01-9Relevant academic research and scientific papers
Discovery of novel arylethynyltriazole ribonucleosides with selective and effective antiviral and antiproliferative activity
Wan, Jinqiao,Xia, Yi,Liu, Yang,Wang, Menghua,Rocchi, Palma,Yao, Jianhua,Qu, Fanqi,Neyts, Johan,Iovanna, Juan L.,Peng, Ling
, p. 1144 - 1155 (2009)
Novel ethynyltriazole ribonucleosides were synthesized using a simple and efficient two-step procedure involving Sonogashira coupling and subsequent ammonolysis. Compounds 2f and 3o inhibited hepatitis C virus (HCV) replication efficiently, whereas compou
NOVEL VIRAL REPLICATION INHIBITORS
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Page/Page column 35, (2009/03/07)
The present invention relates to novel compounds and to their use as a medicament, more in particular for the treatment or prevention of viral infections in mammals. The invention also relates to processes for the preparation of compounds according to the
