110683-03-9Relevant articles and documents
A simple, general and efficient method for O and N-retinoylation. Application to the synthesis of 2-retinoyl-lecithin
Sangmam, Charles,Winum, Jean-Yves,Lucas, Marc,Montero, Jean-Louis,Chavis, Claude
, p. 2945 - 2958 (2007/10/03)
The synthesis of the new 1-stearoyl-2-retinoyl-glycero-3- phosphorylcholine by coupling of retinoic acid and lysolecithin with DCC- DMAP (1.2 eq.) is reported. This method is applied to O and N-retinoylation of uncharged organic substrates such as aliphatic alcohols, free hydroxyl anomeric sugars, aromatic amines and C-protected α-aminoacids.
N-(retinoyl)amino acids, synthesis and chemopreventive activity in vitro
Shealy,Frye,Schiff
, p. 190 - 196 (2007/10/02)
N-(all-trans-Retinoyl)amino acids were synthesized via all-trans-retinoyl chloride and an ester of the amino acid. The retinoyl derivatives of leucine, phenylalanine, alanine, tyrosine, and glutamic acid were prepared. The 13-cis-retinoyl derivatives of l