110683-23-3

Basic information

• Product Name: 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran
• Synonyms: 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran Hydrochloride;8-Amino-2-(2H-tetrazol-5-yl)-4H-1-benzopyran-4-one hydrochloride;8-aMino-2-(1,2,3,4-tetrazol-5-yl)-4H-chroMen-4-one hydrochloride;8-aMino-2-(1H-tetrazol-5-yl)-4H-chroMen-4-one hydrochloride;8-Amino-2-(2H-tetrazol-5-yl)-4H-chromen-4-one hydrochloride;4H-1-Benzopyran-4-one, 8-aMino-2- (2H-tetrazol-5-yl)-, hydrochloride;8-Amino-2-(5-tetrazolyl)-4-oxo-4(H)-1-benzopyran hydrochloride;8-Amino-4-oxo-2-(tetrazol-5-yl)-4H-1-benzopyran HCl
• CAS NO: 110683-23-3
• Molecular Formula: C10H7N5O2
• Molecular Weight: 229.19488
• EINECS: -0
• Mol File: 110683-23-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 515 °C at 760 mmHg
• Flash Point: 265.2 °C
• Appearance: /
• CAS DataBase Reference: 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran(110683-23-3)
• EPA Substance Registry System: 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran(110683-23-3)

Safety Data

• Hazardous Substances Data: 110683-23-3(Hazardous Substances Data)

Usage

General Description

8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran is a chemical compound with the molecular formula C10H8N6O2. It is a derivative of benzopyran, containing an amino group and a tetrazolyl group. 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran has potential pharmacological properties, and research has shown that it may have anticancer, anti-inflammatory, and antimicrobial activities. It is also being studied for its potential use in treating neurodegenerative diseases and as a component in drug development. 8-Amino-4-oxo-2-tetrazol-5-yl-4H-1-benzopyran has the potential to be a valuable compound in medicinal chemistry and drug discovery.

Upstream product

• 110683-75-5 ethyl 8-nitro-4-oxo-4H-benzopyran-2-carboxylate 
• 161369-34-2 8-nitro-4-oxo-4H-1-benzopyran-2-carboxamide 
• 141283-41-2 8-nitro-4-oxo-4H-1-benzopyran-2-carbonitrile 
• 141283-42-3 8-nitro-4-oxo-2-(5-1H-tetrazolyl)-4H-1-benzopyran 

Downstream Products

• 103177-37-3 pranlukast 

Relevant articles and documents

New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships

(p-Amylcinnamoyl)anthranilic acid (3a) had moderate antagonist activities against LTD4-induced smooth muscle contraction on guinea pig ileum and LTC4-induced bronchoconstriction in anesthetized guinea pigs. Modifications were made in the hydrophobic part (cinnamoyl moiety) and the hydrophilic part (anthranilate moiety) of 3a. A series of 8-(benzoylamino)-2-tetrazol-5-yl-1,4-benzodioxans and 8-(benzoylamino)-2-tetrazol-5-yl-4-oxo-4H-1-benzopyrans were revealed to be potent antagonists of leukotrienes C4 and D4. Among both series, ONO-RS-347 (18k) and ONO-RS411 (19h) were the most potent and orally active antagonists, respectively. Structure-activity relationships are discussed.