110697-46-6Relevant articles and documents
Poly-α,β-aspartyl-Arg-Gly-Asp-Phe: A novel polymeric nanomedicine
Chen, Shuangling,Wang, Yuji,Li, Shan,Wang, Yaonan,Zhao, Ming,Zhu, Haimei,Wu, Jianhui,Peng, Shiqi
, p. 182 - 186 (2015)
Thrombosis is a pathological condition and has been one of the most prominent causes of morbidity and mortality. Poly-α,β-aspartic acid is a biodegradable polymer, and RGD-tetrapeptides target thrombus. These led to the design of poly-α,β-aspartyl-Arg-Gly
Improved anti-osteoporosis potency and reduced endometrial membrane hyperplasia during hormone replacement therapy with estrogen-RGD peptide conjugates
Xiong, Yu,Zhao, Ming,Wang, Chao,Heng, Wei Chang,Peng, Shiqi
, p. 3340 - 3353 (2008/02/12)
To improve the specificity and potency of estrogen replacement therapy therapeutics while also minimizing the side effects such as bone resorption and thickening of the uterine wall, a series of novel estrogen-derived conjugates estradiol-3-RGD, estradiol
Derivatives of N-amidinoproline and their use in conventional and solid phase peptide synthesis
Burov,Moskalenko,Leko,Dorosh,Panarin
, p. 509 - 516 (2008/02/08)
N-Amidinoproline, a hybrid structure modeling key features of the Arg-Pro sequence, was synthesized. The activation of carboxyl group of free N-amidinoproline was found to result in the formation of a cyclic side product, whose structure was confirmed by