1107016-44-3Relevant academic research and scientific papers
Chiral benzene phthalide compound and synthesis method of deuterated compound thereof (by machine translation)
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Paragraph 0063-0065, (2020/05/01)
The method, comprises the following steps: dissolving a rhodium metal catalyst, zinc powder, additive and a ligand in a drying solvent under an inert gas atmosphere, then adding 3 - alkylene phthalate compound or 3 -arylphthalic acid ester compound reaction substrate, to react under 40-70 °C to obtain the target product, and the reaction formula is as follows : . The kit is cheap and easily available, simple, operation, convenient,atom economy, is suitable for carrying out routine preparation. (by machine translation)
A superhydrophobic mesostructured silica as a chiral organometallic immobilization platform for heterogeneous asymmetric catalysis
Han, Bing,Zhao, Lei,Song, Yongkang,Zhao, Zhongrui,Yang, Dongfeng,Liu, Rui,Liu, Guohua
, p. 2920 - 2927 (2018/06/14)
Immobilization of molecular catalysts in a superhydrophobic material can efficiently overcome the shortage of low catalytic efficiency in heterogeneous catalysis. In this study, by taking advantage of a superhydrophobic mesostructured silica as a support,
A Polymer-Coated Rhodium/Diamine-Functionalized Silica for Controllable Reaction Switching in Enantioselective Tandem Reduction-Lactonization of Ethyl 2-Acylarylcarboxylates
Kong, Lingyu,Zhao, Junwei,Cheng, Tanyu,Lin, Jingrong,Liu, Guohua
, p. 2244 - 2249 (2016/04/26)
The design of a smart heterogeneous catalyst for controllable reaction switching is highly desirable in asymmetric catalysis. In this work, by taking advantage of the thermoresponsive behavior of a water-soluble polymer coating and the confined feature of
Hollow-shell-structured nanospheres: A recoverable heterogeneous catalyst for rhodium-catalyzed tandem reduction/lactonization of ethyl 2-acylarylcarboxylates to chiral phthalides
Liu, Rui,Jin, Ronghua,An, Juzeng,Zhao, Qiankun,Cheng, Tanyu,Liu, Guohua
supporting information, p. 1388 - 1394 (2014/05/06)
Chiral organorhodium-functionalized hollow-shell-structured nanospheres were prepared by immobilization of a chiral N-sulfonylated diamine-based organorhodium complex within an ethylene-bridged organosilicate shell. Structural analysis and characterization reveal its well-defined single-site rhodium active center, and transmission electron microscopy images reveal a uniform dispersion of hollow-shell-structured nanospheres. As a heterogenous catalyst, it exhibits excellent catalytic activity and enantioselectivity in synthesis of chiral phthalides by a tandem reduction/lactonization of ethyl 2-acylarylcarboxylates in aqueous medium. The high catalytic performance is attributed to the synergistic effect of the high hydrophobicity and the confined chiral organorhodium catalytic nature. The organorhodium-functionalized nanospheres could be conveniently recovered and reused at least 10 times without loss of catalytic activity. This feature makes it an attractive catalyst in environmentally friendly organic reactions. The results of this study offer a new approach to immobilize chiral organometal functionalities within the hollow-shell-structured nanospheres to prepare materials with high activity in heterogeneous asymmetric catalysis. Shell strategy: Hollow-shell-structured chiral organorhodium-functionalized nanospheres present excellent catalytic efficiency in the aqueous asymmetric synthesis of chiral phthalides by a tandem reduction/lactonization reaction of 2-acylarylcarboxylates (see figure). The superior catalytic performance and the enhanced enantioselectivity are attributed to the salient hydrophobic function of nanospheres and confined chiral catalytic nature of the organorhodium functionality.
Catalytic enantioselective synthesis of chiral phthalides by efficient reductive cyclization of 2-acylarylcarboxylates under aqueous transfer hydrogenation conditions
Zhang, Bo,Xu, Ming-Hua,Lin, Guo-Qiang
supporting information; experimental part, p. 4712 - 4715 (2009/12/08)
A new diamine ligand for asymmetric transfer hydrogenation (ATH) was discovered. The reductive cyclization of 2-acylarylcarboxylates was found to proceed highly stereoselective by the new Ru complex-catalyzed ATH and subsequent In situ lactonization under aqueous conditions. It enables efficient access to a wide variety of 3-substituted phthalides In enantiomerically pure form.
