1107060-58-1

Basic information

• Product Name: 1-(4-bromobenzoyl)cyclopropane-2,3-dicarboxylic acid diethyl ester
• Synonyms: 1-(4-bromobenzoyl)cyclopropane-2,3-dicarboxylic acid diethyl ester
• CAS NO: 1107060-58-1
• Molecular Weight: 369.212
• Mol File: 1107060-58-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-bromobenzoyl)cyclopropane-2,3-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromobenzoyl)cyclopropane-2,3-dicarboxylic acid diethyl ester(1107060-58-1)
• EPA Substance Registry System: 1-(4-bromobenzoyl)cyclopropane-2,3-dicarboxylic acid diethyl ester(1107060-58-1)

Safety Data

• Hazardous Substances Data: 1107060-58-1(Hazardous Substances Data)

Upstream product

• 1146142-22-4 Br^(1-)*C₆H₁₃O₃S⁽¹⁺⁾ 
• 35338-15-9 (E)-ethyl 4-(4-bromophenyl)-4-oxo-but-2-enoate 

Downstream Products

• 1107060-63-8 1-(4-bromobenzoyl)-cyclopropane-2,3-dicarboxylic acid bis[(2-hydroxyethyl)amide] 

Relevant articles and documents

Design, synthesis and conformational analysis of turn inducer cyclopropane scaffolds: microwave assisted amidation of unactivated esters on catalytic solid support to obtain γ-turn mimic scaffolds

Novel constrained 1-aroyl-cyclopropane-2,3-cis-dicarboxylic acid bis-[(2-hydroxy-ethyl)-amides] (17a-e) with varied torsional angles have been synthesized in high yield from unactivated esters of 1-aroyl-2,3-cis-diethoxycarbonylcyclopropanes (15a-e) on a catalytic solid support with reduced reaction times by using the monomode-microwave irradiation; 15a-e were obtained by diastereoselective ethoxycarbonylmethylene transfer from a sulfur ylide to ethyl β-aroylacrylates (10a-e). Torsional angles and interatomic distance measurements on the energy minimized structures of the obtained molecules (17a-e, DFT, B3LYP/6-31G* level) have established these molecules as valuable γ-turn mimic scaffolds.