1107062-53-2

Upstream product

• 1107062-52-1 (2RS,3R,4R)-3-allyloxy-4-(benzyloxy)hex-5-ene-1,2-diol 

Downstream Products

• 1107062-59-8 (2R,3R)-3-(benzyloxy)-2-(triethylsilyloxymethyl)-3,4-dihydro-2H-pyran 
• 1107062-58-7 (2R,3R)-3-(benzyloxy)-2-(triethylsilyloxymethyl)-3,6-dihydro-2H-pyran 
• 1107062-57-6 (2R,3R)-3-(benzyloxy)-2-(hydroxymethyl)-3,6-dihydro-2H-pyran 
• 1107062-54-3 (2R,3R)-2-allyloxy-1,3-bis(benzyloxy)pent-4-ene 

Relevant academic research and scientific papers

Synthesis of 3-deoxy glycals via tandem metathesis sequences and their use in an intermolecular heck arylation

Deoxy glycals can be synthesized from a mannitol-derived C 2-symmetric diene diol by using the tandem RCM/isomerization approach. Incorporation of a ruthenium-catalyzed dehydrogenative silylation step into the reaction sequence is possible. Thus, an orthogonally protected 3-deoxy glycal results via a tandem RCM/hydrosilylation/isomerization sequence. All ruthenium-catalyzed steps of this tandem sequence occur under distinct conditions, allowing for the selective synthesis of the intermediates. The 3-deoxy glycals obtained via this route undergo a regio- and stereoselective Heck reaction, as exemplified by the synthesis of a C-aryl glycoside. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.